Life Out of Control? Blame Your Neurotransmitters

neural synapseWhen your neurotransmitters are out of balance, it causes problems with focus, memory, mood, cravings, sleep and more. Learn how this happens and what to do about it …

Is there an area of your life where you feel out of control?

Are you a shopaholic, chocoholic, caffeine addict, or worse?

Do you get depressed for no apparent reason, feel overwhelmed by life, have trouble sleeping, or have negative thoughts that you just can’t shake?

It’s very possible that you have a neurotransmitter imbalance.

How Your Brain Cells Communicate

There are about 100 billion neurons in the human brain and these cells communicate with each other via brain chemicals called neurotransmitters. Scientists have found just over 100 of these communication chemicals, but it’s believed they will ultimately discover thousands.

Neurotransmitters control your ability to focus, concentrate, and remember, as well as regulating mood, cravings, addictions, sleep, and more.

It’s estimated that 86% of Americans have suboptimal neurotransmitter levels. (1)

Our modern lifestyle is largely to blame. Stress, poor diet, environmental toxins, drugs (prescription and recreational), alcohol, nicotine, and caffeine can cause neurotransmitter depletion.  

Many brain and memory supplements include amino acids, herbs, and vitamins that are designed to boost the production of one or more neurotransmitters. But there is a big problem with this approach!

If you don’t know which neurotransmitters you need to boost, you might well be taking substances that could make your imbalance even worse!

There are two main kinds of neurotransmitters — excitatory and inhibitory.

Read the descriptions of the top four neurotransmitters below and determine which one sounds most like your situation.

Then you can take the right actions and supplement appropriately to optimize your neurotransmitter balance.

Excitatory Neurotransmitters


Excitatory neurotransmitters keep you productive.

Dopamine helps you get focused. Signs that you need more dopamine are low energy and motivation, low libido, needing pick-me-ups like caffeine, sugar, chocolate, or other stimulants to get through the day .

People low in woman with shopping bagsdopamine have a tendency towards depression or apathy, but get a buzz from shopping or gambling. Their illicit drugs of choice are cocaine, amphetamines, or Ecstasy.

A protein-rich diet is an excellent source for the amino acids needed to create more dopamine. Foods that promote dopamine include avocado, beef, fish, pork, and coffee.

Exercise boosts dopamine levels naturally. 

Try supplementing with the amino acid tyrosine which converts into dopamine.


Acetylcholine is for learning and remembering. When you are low in this brain chemical, you can’t remember, become forgetful, can’t focus, can’t follow plots, and can’t find the right words.

You may crave fatty foods. You probably have poor muscle tone and find it difficult to exercise.

Acetylcholine deficiencies are associated with Alzheimer’s, dementia, and multiple sclerosis. Acetylcholine activity is the target of Alzheimer’s drugs, which block the breakdown of this brain chemical.

A choline-rich diet will help to produce the acetylcholine the brain needs to stay sharp. Some acetylcholine-rich foods include almonds, blueberries, cruciferous vegetables, cheese, eggs, fish, and chicken. 

Brain supplements that naturally increase acetylcholine levels include alpha GPC, CDP-choline, and vitamin B6.

Inhibitory Neurotransmitters


Inhibitory neurotransmitters keep you feeling happy and relaxed. 

If you’re low in GABA (gamma-aminobutyric acid), you may be easily stressed, overstimulated and overwhelmed.

You have a hard time relaxing and slowing down and have trouble sleeping. You may experience heart palpitations, cold hands, and shortness of breath.

woman meditatingGABA-rich foods are bananas, broccoli, fish, organ meats, spinach, and nuts. 

Individuals low in GABA often self-medicate with food, alcohol, or tranquilizing drugs to relax.

They could benefit from taking the amino acids l-theanine, the calming compound found in green tea, and taurine, which activates GABA receptors.

B vitamins reduce the wear and tear of stress, while relaxing herbs like hops, passion flower, valerian, and lemon balm promote a sense of calm and help you sleep.

The probiotic Lactobacillus rhamnosus markedly improves GABA levels. 

It’s been shown that GABA levels can be increased by doing yoga. (2)

GABA supplements are sold, but there is some concern that supplemental GABA doesn’t readily cross the blood-brain barrier. 


Serotonin plays an important part in learning, mood, and sleep.

People low in this substance suffer from anxiety, insomnia, low self-esteem, negative thoughts, OCD, and SAD (seasonal affective disorder).

These people feel better with exercise and when taking selective serotonin reuptake inhibitor (SSRI) drugs, such as Paxil, Prozac, Zoloft, Celexa, and Lexapro.

Signs you are low in serotonin are that you crave sugar, bread and pasta, have trouble sleeping, and are prone to anxiety, negativity, and depression.

Some foods contain serotonin, but it does not cross the blood-brain barrier.

You may have heard that eating foods that contain the amino acid tryptophan can raise serotonin levels, but that’s not what actually happens.

Surprisingly, serotonin levels drop after eating a meal that contains protein. (3)

The relationship between serotonin, tryptophan and food is complicated. Read our discussion about how to how to increase serotonin with food.

Daily exercise, sufficient sleep, and exposure to sunshine will increase serotonin levels, too. 

One of the most amazing things about serotonin is that 90% of it is produced in the intestines, not your brain! (4)

That is why people who fit the profile of low serotonin should consider taking a probiotic supplement to establish healthy gut flora. 

An overabundance of bad bacteria generates toxic byproducts called lipopolysaccharides which have numerous negative effects on your brain including lowered levels of both dopamine and serotonin.

If you are low in serotonin, supplements that can help include 5-HTP, B complex vitamins, magnesium, and a probiotic supplement.

Supplements for Neurotransmitter Balance

Here are supplements that can boost your neurotransmitter production from the companies we use ourselves and recommend to you. 

woman taking vitaminsIf you have signs of being low in either dopamine or acetylcholine try:

  • Wellness Resources Super Brain Booster — contains acetyl-l-tyrosine (a readily absorbable form of tyrosine), vinpocetine, (regulates the flow of neurotransmitters), alpha GPC (highly bioavailable form of choline that forms acetylcholine), and bacopa (naturally balances neurotransmitters)

If you have signs of low GABA try: 

If you have signs of low serotonin try:

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